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IM37

Sigma-Aldrich

Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4)

liquid, clone 56-2A4, Calbiochem®

Sinónimos:

Anti-Gelatinase B, Anti-92 kDa Gelatinase, Anti-Matrix Metalloproteinase 9

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About This Item

Código UNSPSC:
12352203

origen biológico

mouse

Nivel de calidad

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

56-2A4, monoclonal

formulario

liquid

contiene

≤0.1% sodium azide as preservative

reactividad de especies

human, rabbit, rat, guinea pig

no debe reaccionar con

hamster, mouse, bovine

fabricante / nombre comercial

Calbiochem®

condiciones de almacenamiento

OK to freeze
avoid repeated freeze/thaw cycles

isotipo

IgG1

Condiciones de envío

wet ice

temp. de almacenamiento

−20°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... MMP9(4318)

Descripción general

Purified mouse monoclonal antibody (see application references). Recognizes both the ~92 kDa latent and the ~83 kDa active forms of MMP-9.
Recognizes the ~92 kDa latent and the ~83 kDa active forms of MMP-9 in breast carcinoma tissue.
This Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of MMP-9 (Ab-3).

Inmunógeno

Human
a synthetic peptide corresponding to amino acids 626-644 of human MMP-9

Aplicación


Frozen Sections (see application references)
Immunoblotting (1 g/ml)
Paraffin Sections (see application references)

Envase

Please refer to vial label for lot-specific concentration.

Advertencia

Toxicity: Standard Handling (A)

Forma física

In 100 mM sodium phosphate buffer, 0.1% BSA, pH 7.0

Reconstitución

Following initial thaw, aliquot and freeze (-20°C).

Nota de análisis

Negative Control
MMP-2 protein (Cat. Nos. PF023 or PF037)
Positive Control
MMP-9 protein (Cat. Nos. PF024 or PF038) or breast carcinoma tissue

Otras notas

Cottam, D.W. and Rees, R.C. 1993. Intl. J. Oncol.2, 861.
Stetler-Stevenson, W.G., et al. 1993. FASEB J.7, 1434.
Okada, Y., et al., 1992. J. Biol. Chem.267, 21712.
Woessner, J.F. 1991. FASEB J.5, 2145.
Liotta, L.A. and Stetler-Stevenson, W.G. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1, 99.
This antibody does not react with MMP-1, MMP-2, MMP-3 or MMP-13. Antibody should be titrated for optimal results in individual systems.

Información legal

Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Nezam Haider et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 16(5), 753-762 (2009-08-08)
Macrophage apoptosis and MMP activity contribute to vulnerability of atherosclerotic plaques to rupture. By employing molecular imaging techniques, we investigated if apoptosis and MMP release are interlinked. Atherosclerosis was produced in rabbits receiving high-cholesterol diet (HC), who underwent dual radionuclide
Fábio Montico et al.
Anatomical record (Hoboken, N.J. : 2007), 296(11), 1758-1767 (2013-10-10)
The influence of senescence and hormone replacement on the onset of pathologic processes in the prostate is not yet fully understood. The aim was to identify the immunoreactivity and protein levels of molecules involved in cell proliferation, tissue remodeling and
Shinichiro Fujimoto et al.
Journal of the American College of Cardiology, 52(23), 1847-1857 (2008-11-29)
This study sought to evaluate the feasibility of noninvasive detection of matrix metalloproteinase (MMP) activity in experimental atherosclerosis using technetium-99m-labeled broad matrix metalloproteinase inhibitor (MPI) and to determine the effect of dietary modification and statin treatment on MMP activity. The
Satoru Ohshima et al.
Journal of the American College of Cardiology, 55(12), 1240-1249 (2010-03-20)
Technetium-99m-labeled matrix metalloproteinase inhibitor (MPI) was used for the noninvasive assessment of matrix metalloproteinase (MMP) activity in atherosclerotic plaques after minocycline (MC) intervention. MMP activity in atherosclerosis contributes to plaque instability. Some antimicrobial agents may attenuate MMP activity. Atherosclerotic lesions
Javier García-Solares et al.
Fertility and sterility, 110(7), 1318-1327 (2018-12-07)
To study the mechanisms of invasion and innervation of deep endometriosis in women. Morphologic and immunohistochemical analysis of human endometriotic lesions. Academic research unit. Seventeen biopsy samples of deep endometriotic lesions were collected from patients undergoing surgery for deep endometriosis.

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