GF037

Thrombopoietin, human

>98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized, suitable for cell culture

• Sinónimos: TPO
• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

Propiedades

• Nombre del producto: Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.
• origen biológico: human
• Nivel de calidad: 100
• Ensayo: >98% (SDS-PAGE and HPLC)
• actividad específica: ≥1x10(e6) U/mg
• fabricante / nombre comercial: Chemicon^®
• técnicas: cell culture | mammalian: suitable
• impurezas: <0.1 ng/mg Endotoxin (of human TPO; 1 EU/μg)
• entrada: sample type hematopoietic stem cell(s)
• Nº de acceso NCBI: NM_000460.2; NM_199228.1; NM_199356.1
• Nº de acceso UniProt: P40225
• Condiciones de envío: dry ice
• Información sobre el gen: human ... TPO(7173)

Descripción

Descripción general

Product Source: E.coli

TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. Chemicon′s Human TPO is a soluble 18.5 kDa protein containing 174 amino acid residues which comprises the receptor binding domain of the Mpl-ligand protein.

Acciones bioquímicas o fisiológicas

The ED50 was determined by the dose-dependent stimulation of the proliferation of M07e cells is ≤1.0 ng/mL

Forma física

Lyophilized protein from 5mM Tris, pH 7.6, with no additives.

Almacenamiento y estabilidad

The lyophilized powder, though stable at room temperature, is best stored at -20°C. Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.5-1.0 mg/mL. This solution can be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted TPO should be stored in working aliquots at -20°C.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1