FCMAB418PE-I

Milli-Mark^® Anti-CAR-PE Antibody, clone RmcB

clone RmcB, Milli-Mark^®, from mouse

• Sinónimos: 46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3 binding protein, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, coxsackie virus B receptor, coxsackie virus and adenovirus receptor
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: PE
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: RmcB, monoclonal
• reactividad de especies: human
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• isotipo: IgG1
• Nº de acceso NCBI: NP_001329
• Nº de acceso UniProt: P78310
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CXADR(1525)

Descripción

Descripción general

The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR′s biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation.

Especificidad

Antibody recognizes CAR.

Inmunógeno

Native human coxsackie virus-adenovirus receptor protein

Aplicación

Detect CAR using this Milli-Mark Anti-CAR-PE Antibody, clone RmcB validated for use in FC.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Calidad

Evaluated by flow cytometry using HT-29 cells.

Descripción de destino

40 kDa Calculated. Uniprot indicates multiple isoforms ranging from 9 to 40 kDa

Forma física

Protein G Purified

Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Almacenamiento y estabilidad

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análisis

Control
HT-29 cells

Otras notas

Unconjugated version Cat. No. 05-644 is known to react with Mouse and Rat.

Información legal

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable