FCMAB255F

Milli-Mark^® Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

clone TC11-18H10.1, Milli-Mark^®, from rat

• Sinónimos: Cytotoxic T-lymphocyte-associated antigen 8
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rat
• conjugado: FITC conjugate
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: TC11-18H10.1, monoclonal
• reactividad de especies: mouse
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_034682
• Nº de acceso UniProt: Q62386
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: mouse ... Il17A(16171)

Descripción

Descripción general

IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.

Especificidad

Antibody recognizes Interleukin-17A.

Inmunógeno

Recombinant protein corresponding to mouse Il17a

Aplicación

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunological Signaling

Calidad

Evaluated by flow cytometry using stimulated EL-4 cells

Descripción de destino

17 kDa Calculated

Forma física

Antigen Affinity Purified

Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Almacenamiento y estabilidad

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análisis

Control
PMA and Ionomycin stimulated EL-4 cells.

Información legal

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable