FCMAB184F

Milli-Mark^® Anti-CD19 -FITC Antibody, clone HD37

clone HD37, Milli-Mark^®, from mouse

• Sinónimos: Differentiation antigen CD19 ; ; B-lymphocyte surface antigen B4 ; ; T-cell surface antigen Leu-12, B-lymphocyte antigen CD19
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Propiedades

• origen biológico: mouse
• Nivel de calidad: 100
• conjugado: FITC conjugate
• forma del anticuerpo: purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: HD37, monoclonal
• reactividad de especies: human
• fabricante / nombre comercial: Milli-Mark^®
• técnicas: flow cytometry: suitable
• isotipo: IgG1κ
• Nº de acceso NCBI: NP_001761.3
• Nº de acceso UniProt: P15391
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... CD19(930)

Descripción

Descripción general

CD19 is a 120 kDa transmembrane glycoprotein with a reduced MW of 95 kDa (Pezzutto, 1987; Sato, 1997). CD19 is a member of the immunoglobulin superfamily with two extracellular C2-type domains (Pezzutto, 1987), and it is a critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation (Sato, 1997). CD19 expression is restricted to B cells, being absent from T cells, monocytes, and granulocytes (Pezzutto, 1987). The CD19 antigen appears early during B cell maturation, probably at late pro-B cell stage around the time of Ig heavy chain rearrangement. It then persists during all stages of B cell maturation and is lost upon terminal differentiation to plasma cells (Pezzutto, 1987).

Especificidad

Antibody recognizes Human CD19.

Inmunógeno

Hairy cell leukemia cells

Aplicación

Detect CD19 using this Milli-Mark Anti-CD19 -FITC Antibody, clone HD37 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Calidad

Evaluated by flow cytometry using Human Lymphocytes

Descripción de destino

120kDa (Pezzutto, 1987; Sato, 1997)

Forma física

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2

Almacenamiento y estabilidad

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Nota de análisis

Control
Human Lymphocytes

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable