ABN58

Anti-phospho MAP1B (Thr1265) Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Microtubule-associated protein 1B, MAP-1B, MAP1(X), MAP1.2, MAP1 light chain LC1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: rat
• reactividad de especies (predicha por homología): mouse (immunogen homology)
• técnicas: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• Nº de acceso UniProt: P14873
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: phosphorylation (pThr1265)
• Información sobre el gen: mouse ... Map1B(17755) ; rat ... Map1B(29456)

Descripción

Descripción general

Microtubule-associated protein 1B (MAP1B) is neuron-specific and is thought to play a part in controlling the neuronal cytoskeleton. MAP1B is made up of heavy and light chains and is involved in the microtubule and actin filament association. MAP1B may have an important role in axon formation by supporting microtubule dynamics and controlling cytoskeletal arrangement. MAP1B has also been associated with Netrin 1 signaling.

Especificidad

Other homologies: Human (91% sequence homology).

This antibody recognizes MAP1B phosphorylated at Thr1265.

Inmunógeno

Epitope: Phosphorylated Thr1265

KLH-conjugated linear peptide corresponding to mouse MAP1B phosphorylated at Thr1265.

Aplicación

Anti-phospho MAP1B (Thr1265) Antibody is an antibody against phospho MAP1B (Thr1265) for use in WB, IH & IC.

Immunohistochemistry Analysis: 1:600 dilution from a representative lot detected MAP1B in embryonic (E12) rat spinal cord tissue. (Image courtesy of Dr. Phillip R. Gordon-Weeks, King′s College London.)

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)

Calidad

Evaluated by Western Blot in S1 rat brain tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.

Descripción de destino

~300 kDa observed

Nota de análisis

Control
S1 rat brain tissue lysate

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable