ABN411

Anti-Aquaporin-4 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse, rat, human
• técnicas: western blot: suitable
• Nº de acceso NCBI: NP_036957
• Nº de acceso UniProt: P47863
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... AQP4(361) ; mouse ... Aqp4(11829) ; rat ... Aqp4(25293)

Descripción

Descripción general

Aquaporin-4 (AQP-4) is also known as Mercurial-insensitive water channel. AQP-4 is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. It is expressed predominantly in the mature brain, but also in the eye, kidney, intestine and lung. AQP-4 is a multi-pass membrane protein that is part of a complex along with MLC1, TRPV4, HEPACAM and ATP1B1.

Especificidad

This antibody recognizes the cytoplasmic domain of Aquaporin-4.

Inmunógeno

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat Aquaporin-4.

Aplicación

Anti-Aquaporin-4 is an antibody targeting the Aquaporin-4 protein, validated for use in WB.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Calidad

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Aquaporin-4 in 10 µg of human brain tissue lysate.

Descripción de destino

~32 kDa observed

Forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human brain tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable