ABC139

Anti-TSPO Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NP_000705.2
• Nº de acceso UniProt: P30536
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... TSPO(706)

Descripción

Descripción general

Translocator protein (TSPO) is also called Mitochondrial benzodiazepine receptor, PKBS, or Peripheral-type benzodiazepine receptor (PBR). TSPO generates peripheral-type benzodiazepine recognition sites. TSPO has a role in cholesterol transport across mitochondrial membranes in steroidogenic cells, and may also be involved in in the transport of porphyrins and heme. TSPO is found in many tissue types, but is normally found expressed at the highest levels in steroid synthesizing tissues.

Especificidad

This antibody recognizes the C-terminus of TSPO.

Inmunógeno

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human TSPO.

Aplicación

Anti-TSPO Antibody is a rabbit polyclonal antibody, validated for use in western blotting & IHC.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western Blotting Analysis: 1.0 µg/mL from a representative lot detected TSPO in 10 µg of HeLa cell lysate.
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected TSPO in human thalamus, human cardiac myocytes and human cerebellum tissue.

Calidad

Evaluated by Western Blotting in human testis tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected TSPO in 10 µg of human testis tissue lysate.

Descripción de destino

~16 kDa observed

Ligadura / enlace

Replaces: MABC650

Forma física

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human testis tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable