AB9610-AF488

Anti-Olig-2 Antibody, Alexa Fluor^™ 488 Conjugate

from rabbit, ALEXA FLUOR^™ 488

• Sinónimos: Oligodendrocyte transcription factor 2, bHLHe19, Olig-2, Oligo2, RACK17, RK17
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• conjugado: ALEXA FLUOR^™ 488
• forma del anticuerpo: purified antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• reactividad de especies: rat, mouse, human
• técnicas: immunofluorescence: suitable
• Nº de acceso NCBI: NM_016967.2
• Nº de acceso UniProt: Q9EQW6
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... OLIG2(10215)

Descripción

Descripción general

Oligodendrocyte transcription factor 2 (UniProt Q9EQW6; also known as bHLHe19, Olig-2, Oligo2, RACK17, RK17) is encoded by the Olig2 (also known as Bhlhb1) gene (Gene ID 50913) in murine species. Olig2 is a basic helix-loop-helix (bHLH) transcription factor expressed in a spinal cord ventricular zone domain where it mediates the sequential generation of motoneurons and oligodendrocytes during embryogenesis. Olig2 also functions as an anti-neurogenic factor in pMN progenitors at early time points to sustain the cycling progenitor pool. The anti-neurogenicity of Olig2 is also responsible for its role in tumorigenesis, especially in brain tumors and leukemia. Due to its expression in glioblastoma and other diffuse gliomas, Olig2 is a useful diagnostic marker of these brain tumors.

Especificidad

The unconjugated antibody (Cat. No. AB9610) recognizes the ~32 kDa Olig-2 protein by Western blotting.

Inmunógeno

Recombinant mouse Olig-2.

Aplicación

Anti-Olig-2 Antibody, Alexa Fluor^™ 488 Conjugate is an antibody against Olig-2 for use in Immunofluorescence.

Research Category
Neuroscience

Research Sub Category
Transcription Factors

The unconjugated antibody (Cat. No. AB9610) is shown to be suitable also for Western blotting, immunocytochemistry, immunohistochemistry, and immunoprecipitation applications.

Calidad

Evaluated by Immunofluorescence in mouse brain tissue.

Immunofluorescence Analysis: A 1:50-100 dilution of this antibody detected Olig-2 in mouse brain tissue sections.

Descripción de destino

~32 kDa observed.

Forma física

Ammonium Sulfate

Purified rabbit polyclonal antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Otras notas

Concentration: Please refer to lot specific datasheet.

Información legal

ALEXA FLUOR is a trademark of Life Technologies

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable