AB5977
Anti-Musashi-1 Antibody
Chemicon®, from rabbit
Sinónimos:
Musashi homolog 1
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
affinity purified immunoglobulin
tipo de anticuerpo
primary antibodies
clon
polyclonal
purificado por
affinity chromatography
reactividad de especies
rodent, mouse, rat, human
fabricante / nombre comercial
Chemicon®
técnicas
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
dry ice
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... MSI1(4440)
Descripción general
In mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, differentiation and tumorigenesis. Musashi1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi1 is a selective marker for intestinal stem or early lineage cells. Musashi1 interacts with the Notch pathway during asymmetric cell division by binding the 3′ UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi1 is present.
Especificidad
Reactivity with other species has not been confirmed.
Recognizes Musashi-1.
Inmunógeno
Synthetic peptide, amino acids 5-21 of Musashi.
Aplicación
Detect Musashi-1 using this Anti-Musashi-1 Antibody validated for use in IC, IH & WB.
Immunohistochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Western blot:
1:200-1:1,000 using ECL.
Optimal working dilutions must be determined by the end user.
1:200-1:1,000 dilution from a previous lot was used.
Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.
Western blot:
1:200-1:1,000 using ECL.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Developmental Neuroscience
RNA Binding Protein (RBP)
Neuronal & Glial Markers
Developmental Neuroscience
RNA Binding Protein (RBP)
Calidad
Routinely evaluated by Western Blot on Human Placenta lysates.
Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.
Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.
Descripción de destino
39 kDa
Ligadura / enlace
Replaces: 03-114; 04-1041
Forma física
ImmunoAffinity Purified
Purified rabbit polyclonal in buffer containing a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Almacenamiento y estabilidad
Stable for 1 year at -80ºC from date of receipt.
Nota de análisis
Control
Mouse cortical neural stem cells (Catalog No. SCR029).
Mouse cortical neural stem cells (Catalog No. SCR029).
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Long-term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions
Shin, Soojung, et al.
Stem Cells, 24, 125-138 (2006)
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration.
Gonzalez, LM; Williamson, I; Piedrahita, JA; Blikslager, AT; Magness, ST
Testing null
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice
Maslov, Alexander Y, et al.
The Journal of Neuroscience, 24, 1726-1733 (2004)
Postnatal epithelial growth of the small intestine in the rat occurs by both crypt fission and crypt hyperplasia.
Adrian G Cummins, Ben J Jones, Fiona M Thompson
Digestive Diseases and Sciences null
Raffaella Scardigli et al.
Stem cells (Dayton, Ohio), 32(9), 2516-2528 (2014-05-09)
Adult neurogenesis is a multistep process regulated by several extrinsic factors, including neurotrophins. Among them, little is known about the role of nerve growth factor (NGF) in the neurogenic niches of the mouse. Here we analyzed the biology of adult
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