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Merck
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Key Documents

AB5735

Sigma-Aldrich

Anti-Neurofilament M Antibody

Chemicon®, from chicken

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

chicken

Nivel de calidad

forma del anticuerpo

purified antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

mouse, human, rat

fabricante / nombre comercial

Chemicon®

técnicas

immunocytochemistry: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... NEFM(4741)
mouse ... Nefm(18040)
rat ... Nefm(24588)

Especificidad

Neurofilament M (NF-M)

Inmunógeno

Recombinant C-terminal extension of rat NF-M, the so-called KE segment.

Aplicación

Anti-Neurofilament M Antibody detects level of Neurofilament M & has been published & validated for use in WB & IC.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Neuronal & Glial Markers
Western blot: 1:5,000-1:10,000

Immunocytochemistry: 1:1,000-1:2,000

Optimal working dilutions must be determined by the end user.

Forma física

Chicken IgY. Liquid containing ~5 mM sodium azide.
Format: Purified

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Código de clase de almacenamiento

10 - Combustible liquids


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Rui O Costa et al.
Cell reports, 28(4), 864-876 (2019-07-25)
Ribosomes and a subset of cellular mRNAs are trafficked into axons of developing neurons. The axonal localization of translational machinery allows new proteins to be rapidly and locally synthesized during axonal growth and pathfinding. However, in mature neurons, axonal ribosomes
Víctor Hugo Cornejo et al.
Cell reports, 30(13), 4505-4517 (2020-04-03)
TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery remains poorly understood. Here we examine the distribution of TRPM8
Niliksha Gunewardene et al.
Stem cells international, 2016, 1781202-1781202 (2016-03-12)
Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged auditory system. Here, we explored the potential of
Directing human induced pluripotent stem cells into a neurosensory lineage for auditory neuron replacement.
Gunewardene, N; Bergen, NV; Crombie, D; Needham, K; Dottori, M; Nayagam, BA
BioResearch Open Access null
Rodrigo López-Leal et al.
Methods in molecular biology (Clifton, N.J.), 1739, 255-267 (2018-03-17)
Sensory neurons from dorsal root ganglion efficiently regenerate after peripheral nerve injuries. These neurons are widely used as a model system to study degenerative mechanisms of the soma and axons, as well as regenerative axonal growth in the peripheral nervous

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