AB5669
Anti-Spinophilin Antibody
Chemicon®, from rabbit
Sinónimos:
Neurabin-II
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
affinity purified immunoglobulin
tipo de anticuerpo
primary antibodies
clon
polyclonal
purificado por
affinity chromatography
reactividad de especies
rat
fabricante / nombre comercial
Chemicon®
técnicas
western blot: suitable
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... PPP1R9B(84687)
Especificidad
Spinophilin
Inmunógeno
Synthetic peptide from rat Spinophilin.
Aplicación
Anti-Spinophilin Antibody detects level of Spinophilin & has been published & validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Neuronal & Glial Markers
Synapse & Synaptic Biology
Neuronal & Glial Markers
Western blot: 0.05 - 0.1 μg/mL using ECL on rat brain lysate. Reacts with a band of ~140 kDa.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Forma física
Affinity purified immunoglobulin. Liquid in 0.02M phosphate buffer containing 0.25M NaCl, pH 7.6 with 0.1% sodium azide.
Almacenamiento y estabilidad
Maintain at 2-8°C in undiluted for up to 6 months after date of receipt.
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Spinophilin loss contributes to tumorigenesis in vivo.
Irene Ferrer,Sandra Peregrino,Marta Ca?amero,Yolanda Cecilia,Carmen Blanco-Aparicio,Amancio Carnero
Cell Cycle null
Micah A Shelton et al.
Biological psychiatry, 78(6), 374-385 (2015-03-31)
Microtubule-associated protein 2 (MAP2) is a neuronal protein that plays a role in maintaining dendritic structure through its interaction with microtubules. In schizophrenia (Sz), numerous studies have revealed that the typically robust immunoreactivity (IR) of MAP2 is significantly reduced across
Eva M Verdugo-Sivianes et al.
Oncotarget, 8(62), 105196-105210 (2017-12-30)
The scaffold protein Spinophilin (Spinophilin, PPP1R9B) is one of the regulatory subunits of phosphatase-1 (PP1), directing it to distinct subcellular locations and targets. The loss of Spinophilin reduces PP1 targeting to pRb, thereby maintaining higher levels of phosphorylated pRb. Spinophilin
Kisho Obi-Nagata et al.
Science advances, 9(23), eade5973-eade5973 (2023-06-09)
Human genetics strongly support the involvement of synaptopathy in psychiatric disorders. However, trans-scale causality linking synapse pathology to behavioral changes is lacking. To address this question, we examined the effects of synaptic inputs on dendrites, cells, and behaviors of mice
Melanie J Grubisha et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(49) (2021-12-02)
Normally, dendritic size is established prior to adolescence and then remains relatively constant into adulthood due to a homeostatic balance between growth and retraction pathways. However, schizophrenia is characterized by accelerated reductions of cerebral cortex gray matter volume and onset
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