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AB5428P

Sigma-Aldrich

Anti-Per2 Antibody

Chemicon®, from rabbit

Sinónimos:

Period Circadian Protein 2

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

mouse

fabricante / nombre comercial

Chemicon®

técnicas

ELISA: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

mouse ... Per2(18627)

Especificidad

Recognizes mouse Per 2. The immunogen shows no significant sequence homology with Per 1 or Per 3.

SPECIES REACTIVITIES: The immunogen sequence has 77% homology with rat Per2. No significant homology is seen with human Per 2 (Nagase et al. 1997). Reactivity with other species has not been confirmed.

Inmunógeno

A 23 amino acid peptide sequence within the C-teriminus of mouse Per 2 (Albretch et al. 1997; Shearman et al. 1997; Sakamoto et al. 1998).

Aplicación

Detect Per2 using this Anti-Per2 Antibody validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Circadian Rhythm & Sleep
Western blot: 1-10 μg/mL using ECL.

ELISA: 50-100 ng of control peptide per well.

Optimal working dilutions must be determined by the end user.

Forma física

Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA and 0.05% sodium azide.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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The molecular circadian clock is based on a transcriptional/translational feedback loop in which the stability and half-life of circadian proteins is of importance. Cysteine residues of proteins are subject to several redox reactions leading to S-thiolation and disulfide bond formation
Xiaoqin Liu et al.
PloS one, 7(11), e50602-e50602 (2012-11-29)
Circadian rhythms in metabolism, physiology, and behavior originate from cell-autonomous circadian clocks located in many organs and structures throughout the body and that share a common molecular mechanism based on the clock genes and their protein products. In the mammalian
Peter Podobed et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(2), R121-R137 (2014-05-03)
Circadian rhythms are essential to cardiovascular health and disease. Temporal coordination of cardiac structure and function has focused primarily at the physiological and gene expression levels, but these analyses are invariably incomplete, not the least because proteins underlie many biological

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