AB3611
Anti-Survivin Antibody
Chemicon®, from rabbit
Sinónimos:
TIAP
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
clon:
polyclonal
application:
WB
reactividad de especies:
mouse
técnicas:
western blot: suitable
citations:
2
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
affinity purified immunoglobulin
tipo de anticuerpo
primary antibodies
clon
polyclonal
purificado por
affinity chromatography
reactividad de especies
mouse
fabricante / nombre comercial
Chemicon®
técnicas
western blot: suitable
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Descripción general
Apoptosis is triggered by a variety of stimuli, including members of the Tumor Necrosis Factor (TNF) family, and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. One of these IAP proteins, Survivin/TIAP, interacts with the processed form of caspase-3 and has been shown to inhibit its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
Especificidad
Detects mouse survivin/TIAP in an approximate 17 kDa band by western blot.
Inmunógeno
Peptide corresponding to aa 128-140 of mouse survivin/TIAP.
Aplicación
Anti-Survivin Antibody is an antibody against Survivin for use in WB.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
BCL2 & Inhibition
Western blot: 1:500 to 1:1000
Mouse spleen tissue lysate can be used as a positive control.
Optimal working dilutions must be determined by end user.
Mouse spleen tissue lysate can be used as a positive control.
Optimal working dilutions must be determined by end user.
Forma física
Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Almacenamiento y estabilidad
Maintain at 4°C for up to 6 months.
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
10 - Combustible liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Yueyang Liu et al.
Oncology letters, 14(1), 525-532 (2017-07-12)
In the present study, the function of S100 calcium binding protein P (S100P) in the C666-1 nasopharyngeal carcinoma (NPC) cell line was examined. The levels of S100P protein in NPC tissues were analyzed using immunohistochemistry, and small interfering RNA silenced
G Ambrosini et al.
Nature medicine, 3(8), 917-921 (1997-08-01)
Inhibitors of programmed cell death (apoptosis) aberrantly prolonging cell viability may contribute to cancer by facilitating the insurgence of mutations and by promoting resistance to therapy. Despite the identification of several new apoptosis inhibitors related to bcl-2 or to the
Angela Raucci et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 22(10), 3716-3727 (2008-07-08)
The receptor for advanced glycation endproducts (RAGE) mediates responses to cell danger and stress. When bound by its many ligands (which include advanced glycation endproducts, certain members of the S100/calgranulin family, extracellular high-mobility group box 1, the integrin Mac-1, amyloid
F Li et al.
Nature, 396(6711), 580-584 (1998-12-22)
Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes, acting to preserve homeostasis and developmental morphogenesis. Although proteins that regulate apoptosis have been implicated in restraining cell-cycle entry and controlling
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