AB3503-I

Anti-PDX-1 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse, human
• técnicas: immunohistochemistry: suitable; western blot: suitable
• Nº de acceso NCBI: NP_000200
• Nº de acceso UniProt: P52945
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... PDX1(3651)

Descripción

Descripción general

Pancreatic and duodenal homeobox 1, also known as PDX1, and Insulin promoter factor 1 is a human gene. This islet-specific protein activates transcription of the insulin andsomatostatin genes. It is a key regulator of islet peptide hormone expressionn and also plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

Especificidad

Recognizes PDX-1

Inmunógeno

KLH-conjugated linear peptide corresponding to region amino acids 90-120 of human PDX-1.

Aplicación

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected pdx-1 in the islets of Langerhans of human and mouse pancreas.

This Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.

Calidad

Evaluated by Western Blotting in mouse pancreatic beta cell tissue lysate.

Western Blotting Analysis: A 1:4,000 dilution of this antibody detected PDX-1 in mouse pancreatic beta cell tissue lysate.

Descripción de destino

~38 kDa observed

Otras notas

Concentration: Please refer to lot specific datasheet.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable