AB3402P

Anti-Agouti Related Protein Antibody

Chemicon^®, from rabbit

• Sinónimos: AGRP
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity purified immunoglobulin
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: mouse
• fabricante / nombre comercial: Chemicon^®
• técnicas: ELISA: suitable; western blot: suitable
• Nº de acceso NCBI: NM_001138.1; NM_007316.1
• Nº de acceso UniProt: O00253
• Condiciones de envío: dry ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... AGRP(181)

Descripción

Descripción general

Agouti-related peptide-expressing (AgRP) neurons seem to be critical for the acute regulation of eating. The AgRP protein is a strong antagonis of MC3-R and MC4-R and is expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.

Especificidad

Recognizes AGRP. The immunogen shows no significant sequence homology with Agouti, tubby, tub, TULP1 or TULP2.

SPECIES REACTIVITIES: The immunogen sequence is 85% homologous with human and bovine. Reactivity with other species has not been confirmed.

Inmunógeno

A 15 amino acid peptide near the C-terminus of mouse AGRP (Shutter et al. 1997; Ollmann et al. 1997).

Aplicación

Detect Agouti Related Protein using this Anti-Agouti Related Protein Antibody validated for use in ELISA & WB.

Research Category
Metabolism

Research Sub Category
Glucose/Glycogen Metabolism

Western blot: 1-10 μg/mL using ECL.



ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Forma física

Liquid in phosphate buffered saline containing 0.1% BSA.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable