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Key Documents

AB3258

Sigma-Aldrich

Anti-Puromycin Sensitive Aminopeptidase Antibody

Chemicon®, from goat

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

goat

Nivel de calidad

forma del anticuerpo

purified immunoglobulin

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

rat, mouse

fabricante / nombre comercial

Chemicon®

técnicas

immunocytochemistry: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... NPEPPS(9520)

Especificidad

Recognizes puromycin sensitive aminopeptidase.

SPECIES REACTIVITIES: It is expected that the antibody may react with other species. Reactivity with other species has not been confirmed.

Inmunógeno

Rat puromycin sensitive aminopeptidase.

Aplicación

Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
This Anti-Puromycin Sensitive Aminopeptidase Antibody is validated for use in WB, IC for the detection of Puromycin Sensitive Aminopeptidase.
Western blot: 1:1,000

Immunocytochemistry: 1:1,000

Optimal working dilutions must be determined by the end user.

Forma física

Format: Purified
Purified immunoglobulin. Liquid in phosphate buffered saline.

Almacenamiento y estabilidad

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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S McLellan et al.
Journal of neurochemistry, 51(5), 1552-1559 (1988-11-01)
An antiserum generated to the soluble form of the rat brain puromycin-sensitive enkephalin-degrading aminopeptidase was used to determine the tissue distribution of the soluble and membrane-associated forms of this enzyme. All tissues examined contained significant levels of the soluble enzyme
Soma Sengupta et al.
Biochemistry, 45(50), 15111-15119 (2006-12-13)
Tau, a microtubule associated protein, aggregates into intracellular paired helical filaments (PHFs) by an unknown mechanism in Alzheimer's disease (AD) and other tauopathies. A contributing factor may be a failure to metabolize free cytosolic tau within the neuron. The buildup
Helena R Zimmermann et al.
Journal of neurochemistry, 146(2), 133-144 (2018-01-18)
Characterization of the molecular signaling pathways underlying protein synthesis-dependent forms of synaptic plasticity, such as late long-term potentiation (L-LTP), can provide insights not only into memory expression/maintenance under physiological conditions but also potential mechanisms associated with the pathogenesis of memory
Helena R Zimmermann et al.
The Journal of clinical investigation, 130(7), 3511-3527 (2020-03-28)
AMPK is a key regulator at the molecular level for maintaining energy metabolism homeostasis. Mammalian AMPK is a heterotrimeric complex, and its catalytic α subunit exists in 2 isoforms: AMPKα1 and AMPKα2. Recent studies suggest a role of AMPKα overactivation

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