AB3203
Anti-Tubulin Antibody, δ 2
Chemicon®, from rabbit
Sinónimos:
Anti-α-tubulin, Tubulin antibody
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About This Item
Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Productos recomendados
origen biológico
rabbit
Nivel de calidad
forma del anticuerpo
affinity purified immunoglobulin
tipo de anticuerpo
primary antibodies
clon
polyclonal
purificado por
affinity chromatography
reactividad de especies
sea urchin, echinoderm, plant
no debe reaccionar con
Saccharomyces cerevisiae
reactividad de especies (predicha por homología)
mammals
fabricante / nombre comercial
Chemicon®
técnicas
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
Nº de acceso NCBI
Nº de acceso UniProt
Condiciones de envío
wet ice
modificación del objetivo postraduccional
unmodified
Información sobre el gen
human ... TUBD1(51174)
Descripción general
Tubulin, the dimeric subunit of microtubules, is submitted to post translational modifications including cyclic tyrosine removal and addition at the COOH terminus of the alpha subunit. The cycle involves two enzymes, TTL (Tubuline Tyrosine Ligase) and Tubulin carboxypeptidase, and generates two major forms: tyrosinated tubulin and detyrosinated tubulin (Glu-tubulin). Removal of the COOH-terminal Glu residue from the alpha chain of Glu-tubulin generates the delta2-tubulin form.
Especificidad
The antibody specifically recognizes the delta 2 form of the tubulin alpha chain (Paturle-Lafanechere et al. 1991).
SPECIES REACTIVITY:
Mammals, sea urchin, plants, not yeast (Lafanechere et al. 1994).
SPECIES REACTIVITY:
Mammals, sea urchin, plants, not yeast (Lafanechere et al. 1994).
Inmunógeno
Peptide corresponding to the C-terminal of delta 2 tubulin.
Aplicación
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
This Anti-Tubulin Antibody, δ 2 is validated for use in IH(P), WB, IC, IH for the detection of Tubulin.
Western blot: 1:1,000
Immunohistochemistry and EM on either frozen or paraffin embedded, fixed tissue (Mialhe et al. 2001): 1:500
Optimal working dilutions must be determined by the end user.
Immunohistochemistry and EM on either frozen or paraffin embedded, fixed tissue (Mialhe et al. 2001): 1:500
Optimal working dilutions must be determined by the end user.
Forma física
Affinity purified immunoglobulin. Liquid in PBS.
Almacenamiento y estabilidad
Maintain at 2-8°C in undiluted for up to 6 months from date of receipt.
Otras notas
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Información legal
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de clase de almacenamiento
12 - Non Combustible Liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Robert O'Hagan et al.
Current biology : CB, 21(20), 1685-1694 (2011-10-11)
Posttranslational modifications (PTMs) such as acetylation, detyrosination, and polyglutamylation have long been considered markers of stable microtubules and have recently been proposed to guide molecular motors to specific subcellular destinations. Microtubules can be deglutamylated by the cytosolic carboxypeptidase CCP1. Loss
Tracy Chong et al.
BMC developmental biology, 11, 69-69 (2011-11-15)
The freshwater planarian Schmidtea mediterranea exhibits two distinct reproductive modes. Individuals of the sexual strain are cross-fertilizing hermaphrodites with reproductive organs that develop post-embryonically. By contrast, individuals of the asexual strain reproduce exclusively by transverse fission and fail to develop
Kinesin-13 and tubulin posttranslational modifications regulate microtubule growth in axon regeneration.
Ghosh-Roy, A; Goncharov, A; Jin, Y; Chisholm, AD
Developmental Cell null
Epigenetic characterization of the vegetative and floral stages of azalea buds: dynamics of DNA methylation and histone H4 acetylation.
Monica Meijon,Luis Valledor,Estrella Santamaria,Pilar S Testillano,Ma Carmen Risue?o et al.
Journal of Plant Physiology null
Isolation rearing induces recognition memory deficits accompanied by cytoskeletal alterations in rat hippocampus.
Bianchi, M, et al.
The European Journal of Neuroscience, 24, 2894-2902 (2006)
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