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Key Documents

AB15708A4

Sigma-Aldrich

Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate | AB15708A4

from rabbit, ALEXA FLUOR 488

Sinónimos:

Tubulin beta-4, Tubulin beta-III, tubulin, beta 3, tubulin, beta, 4

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

conjugado

ALEXA FLUOR 488

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

rat, mouse

reactividad de especies (predicha por homología)

human (based on 100% sequence homology)

técnicas

immunocytochemistry: suitable
immunohistochemistry: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... TUBB3(10381)
mouse ... Tubb3(22152)
rat ... Tubb3(246118)

Descripción general

Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

Especificidad

This antibody recognizes Beta III Tubulin.

Inmunógeno

Synthetic linear peptide corresponding to human Beta III Tubulin.

Aplicación

Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.
Research Category
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism

Calidad

Evaluated by Immunocytochemistry in rat E18 cortex cells.

Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.

Descripción de destino

50 kDa calculated

Forma física

Affinity purified
Purified rabbit polyclonal conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Rat E18 cortex cells

Información legal

ALEXA FLUOR is a trademark of Life Technologies

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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