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AB10618

Sigma-Aldrich

Anti-BAL Antibody

Chemicon®, from rabbit

Sinónimos:

B-aggressive lymphoma

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human

fabricante / nombre comercial

Chemicon®

técnicas

immunoprecipitation (IP): suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... PARP9(83666)

Descripción general

BAL (B-aggressive lymphoma) is a novel risk-related gene that is expressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) than in cured low-risk tumors. The major BAL cDNA encodes a 88 kDa nuclear protein. BAL-overexpressing B-cell lymphoma transfectants have significantly higher rates of migration than vector-only transfectants, indicating that the risk-related BAL gene promotes malignant B-cell migration.

Especificidad

Reactivity has been confirmed in with human Farage non-Hodgkin′s B-cell lymphoma and human BC-1 B-lymphocyte lymphoma lysates.
Recognizes BAL.

Inmunógeno

Synthetic peptide derived from the C-terminal region of the short isoform of human BAL protein (B-aggressive lymphoma, poly (ADP-ribose) polymerase family member 9, PARP9).

Aplicación

Anti-BAL Antibody is an antibody against BAL for use in IP & WB.
Research Category
Apoptosis & Cancer

Epigenetics & Nuclear Function
Research Sub Category
Tumor Markers

Transcription Factors
Western blotting: 1-3 μg/mL
Immunoprecipitation: 7 μg/ reaction

Forma física

Format: Purified
ImmunoAffinity Purified
This polyclonal antibody is supplied in 400 μL of phosphate buffered saline (pH 7.4) containing 0.1% sodium azide.

Almacenamiento y estabilidad

Store at -20°C in undiluted aliquots for 1 year from date of shipment.

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Información legal

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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R C Aguiar et al.
Blood, 96(13), 4328-4334 (2000-12-09)
Clinical risk factor models such as the International Prognostic Index are used to identify diffuse large B-cell lymphoma (DLB-CL) patients with different risks of death from their diseases. To elucidate the molecular bases for these observed clinical differences in outcome
Samia B Bachmann et al.
Molecular cancer, 13, 125-125 (2014-06-03)
Prostate cancer (PCa) is one of the leading causes of cancer-related mortality and morbidity in the aging male population and represents the most frequently diagnosed malignancy in men around the world. The Deltex (DTX)-3-like E3 ubiquitin ligase (DTX3L), also known
Junji Xing et al.
Nature communications, 12(1), 2681-2681 (2021-05-13)
Innate immune cells are critical in protective immunity against viral infections, involved in sensing foreign viral nucleic acids. Here we report that the poly(ADP-ribose) polymerase 9 (PARP9), a member of PARP family, serves as a non-canonical sensor for RNA virus

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