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Key Documents

AB10526

Sigma-Aldrich

Anti-COX4 Antibody

from rabbit, purified by affinity chromatography

Sinónimos:

cytochrome c oxidase subunit IV isoform 1, cytochrome c oxidase subunit IV1, Cytochrome c oxidase polypeptide IV, cytochrome c oxidase subunit 4 isoform 1, mitochondrial

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human

envase

antibody small pack of 25 μg

técnicas

immunohistochemistry: suitable (paraffin)
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

ambient

temp. de almacenamiento

2-8°C

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... COX4I1(1327)

Descripción general

Cytochrome C oxidase subunit 4 (COX4), is one of 13 subunits of cytochrome c oxidase. Cytochrome c oxidase is responsible for catalyzing the last step of electron transfer through the respiratory chain on the mitochondrial inner membrane. COX4 assembles into sub-complexes with other subunits of cytochrome c oxidase and may represent a rate-limiting intermediate.

Especificidad

Other homologies: Rat and mouse (59% sequence homology).

Inmunógeno

KLH-conjugated linear peptide corresponding to human COX4.

Aplicación

Anti-COX4 Antibody detects level of COX4 & has been published & validated for use in WB, IH(P).
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected COX4 in normal human cardiac muscle tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Calidad

Evaluated by Western Blot in human fetal skeletal muscle tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected COX4 in 10 µg of human fetal skeletal muscle tissue lysate.

Descripción de destino

~17 kDa observed.
A non-specific band may be observed at ~58 kDa

Forma física

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Human fetal skeletal muscle tissue lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Artículos

Loading controls in western blotting application.

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