AB10514P

Anti-Serotonin Transporter Antibody

1 mg/mL, from rabbit

• Sinónimos: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, sodium-dependent serotonin transporter, serotonin transporter, Solute carrier family 6 member 4, Na+/Cl- dependent serotonin transporter, 5HT transporter, 5-hydroxytryptamine tr
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies (predicha por homología): sheep (100% homology), rat (100% homology), bovine (100% homology), monkey (100% homology), human (100% homology), horse (100% homology), mouse (100% homology), chimpanzee (100% homology)
• concentración: 1 mg/mL
• técnicas: western blot: suitable
• Nº de acceso UniProt: P31645
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... HTT(3064)

Descripción

Descripción general

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Especificidad

Other species have not been tested.

The antibody reacts with the 70 kDa serotonin transporter protein.

Inmunógeno

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Aplicación

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Calidad

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

Descripción de destino

70 kDa

Ligadura / enlace

Replaces: AB1594P

Forma física

Antigen Affinity Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Almacenamiento y estabilidad

Store at 2-8°C for 1 year from date of receipt.

Nota de análisis

Control
Western Blot : Human lung lysate.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable