8.55137

PAL-NovaSyn TG resin

Novabiochem^®

• Código UNSPSC: 13111023
• NACRES: NA.22

Propiedades

• Nivel de calidad: 200
• Línea del producto: NovaSyn^® TG; Novabiochem^®
• Formulario: beads
• idoneidad de la reacción: reaction type: Fmoc solid-phase peptide synthesis
• fabricante / nombre comercial: Novabiochem^®
• aplicaciones: peptide synthesis
• grupo funcional: amine
• temp. de almacenamiento: 2-8°C

Descripción

Descripción general

PAL-NovaSyn TG resin consists of Barany′s aminomethyl-dimethoxyphenoxyvaleric acid linker ^[1] attached to NovaSyn TG resin. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker ^[2]. There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Nota de análisis

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.30 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer metrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Información legal

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable