8.52245

Fmoc-D-Thr(PO(OBzl)OH)-OH

Novabiochem^®

• Sinónimos: Fmoc-D-Thr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphothreonine
• Fórmula empírica (notación de Hill): C₂₆H₂₆NO₈P
• Número de CAS: 937171-63-6
• Peso molecular: 511.46
• Código UNSPSC: 12352209

Propiedades

• Línea del producto: Novabiochem^®
• Análisis: ≥90.0% (acidimetric); ≥95.0% (HPLC); ≥97% (TLC)
• formulario: powder
• idoneidad de la reacción: reaction type: Fmoc solid-phase peptide synthesis
• fabricante / nombre comercial: Novabiochem^®
• aplicaciones: peptide synthesis
• grupo funcional: Fmoc
• temp. de almacenamiento: 15-25°C

Descripción

Descripción general

An excellent building block for the preparation of D-phosphothreonine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOP^® and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Fmoc SPPS of Peptides containing Post-Translational Modifications

Ligadura / enlace

Replaces: 04-13-1079

Nota de análisis

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): +3.5 - +6.5 °
Purity (TLC(CMA1)): ≥ 97 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 2.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Información legal

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable