8.52036

Fmoc-Hyp(tBu)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Sinónimos: Fmoc-Hyp(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-trans-4-hydroxyproline
• Fórmula empírica (notación de Hill): C₂₄H₂₇NO₅
• Número de CAS: 122996-47-8
• Peso molecular: 409.47
• Número MDL: MFCD00151930
• Código UNSPSC: 12352209
• NACRES: NA.22

Propiedades

• product name: Fmoc-Hyp(tBu)-OH, Novabiochem^®
• Nivel de calidad: 200
• Línea del producto: Novabiochem^®
• Análisis: ≥95.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• formulario: powder
• idoneidad de la reacción: reaction type: Fmoc solid-phase peptide synthesis
• fabricante / nombre comercial: Novabiochem^®
• mp: 63 °C
• aplicaciones: peptide synthesis
• grupo funcional: hydroxyl
• temp. de almacenamiento: 15-25°C
• InChI: 1S/C24H27NO5/c1-24(2,3)30-15-12-21(22(26)27)25(13-15)23(28)29-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,27)/t15-,21+/m1/s1
• Clave InChI: WPBXBYOKQUEIDW-VFNWGFHPSA-N

Descripción

Descripción general

Standard building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Aplicación

• Rational design of plant hairpin-like peptide EcAMP1: Structural–functional correlations to reveal antibacterial and antifungal activity: Discusses the use of Fmoc-Hyp(tBu)-OH in designing peptides that exhibit significant antibacterial and antifungal properties (Barashkova et al., 2022).

Ligadura / enlace

Replaces: 04-12-1078

Nota de análisis

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.50 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Información legal

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable