559276

Ryanodine

≥98% (HPLC), solid, Ca2+ release blocker, Calbiochem^®

• Sinónimos: Ryanodine, High Purity
• Fórmula empírica (notación de Hill): C₂₅H₃₅NO₉
• Número de CAS: 15662-33-6
• Peso molecular: 493.55
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• product name: Ryanodine, High Purity, Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum.
• Nivel de calidad: 100
• Análisis: ≥98% (HPLC)
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: white
• solubilidad: water: 1 mg/mL; methanol: 20 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 10-30°C
• InChI: 1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1
• Clave InChI: JJSYXNQGLHBRRK-YSOSZROBSA-N

Descripción

Descripción general

Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle.

Naturally occurring alkaloid that blocks the release of Ca²⁺ from the sarcoplasmic reticulum. Has many complex effects on Ca²⁺ transport and action in muscle. Purified from Ryanodine Mixture.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
Ca2+ transport and action in muscle

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Harmful (C)

Reconstitución

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Otras notas

Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci.14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res.56, 133.
Sukto, J.L., et al. 1985. Fed. Proc.44, 2984.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS07,GHS09
• Palabra de señalización: Warning
• Frases de peligro: H302 + H312,H410
• Consejos de prudencia: P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable