528175

Plasminogen, Human Plasma

• Sinónimos: Plasminogen, Human Plasma, Profibrinolysin, Plasma Trypsinogen
• Número de CAS: 9001-91-6
• Número MDL: MFCD00131922
• Código UNSPSC: 12352202
• NACRES: NA.25

Propiedades

• origen biológico: human plasma
• Nivel de calidad: 100
• descripción: Merck USA index - 14, 7521
• Ensayo: ≥95% (SDS-PAGE)
• Formulario: lyophilized
• actividad específica: ≥120 units/mg protein
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• solubilidad: water: soluble
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

Native plasminogen from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.

Native plasminogen from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. Plasminogen is converted to the active protease by cleavage at Arg⁵⁶⁰.

Advertencia

Toxicity: Irritant (B)

Definición de unidad

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Arg ethyl ester in 30 min at 37°C, pH 8.0.

Forma física

Lyophilized from 20 mM Tris-HCl, 2 mM EDTA, pH 7.5.

Nota de preparación

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 2 months at -20°C.

Otras notas

Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3