5.09455

Etomoxir

≥98% (HPLC), liquid, CPT-1 inhibitor, Calbiochem^®

• Sinónimos: InSolution Etomoxir, R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate
• Fórmula empírica (notación de Hill): C₁₅H₁₈ClO₄ · Na
• Número de CAS: 828934-41-4
• Peso molecular: 320.74
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• product name: Etomoxir, InSolution, ≥98%, 50 mM aqueous solution, shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity
• Nivel de calidad: 100
• Análisis: ≥98% (HPLC)
• formulario: liquid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; avoid repeated freeze/thaw cycles; protect from light
• temp. de almacenamiento: −70°C
• InChI: 1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1
• Clave InChI: RPACBEVZENYWOL-XFULWGLBSA-M

Descripción

Descripción general

A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells at a concentration of 1-80 µM and 40 µM, respectively.

Acciones bioquímicas o fisiológicas

Primary Target
CPT1

Envase

Packaged under inert gas

Advertencia

Toxicity: Standard Handling (A)

Forma física

A 50 mM (2 mg/118 µL) solution of Etomoxir (Cat. No. 236020) in H₂O.

Reconstitución

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Otras notas

Xu, F.Y., et al. 2003. J. Lipid Res.44, 415.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable