5.08052

iMDK

≥98% (HPLC), solid, midkine inhibitor, Calbiochem^®

• Sinónimos: Midkine Inhibitor, iMDK, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one, 3-(2-(4-Fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl)-2H-chromen-2-one, MDK Expression Inhibitor
• Fórmula empírica (notación de Hill): C₂₁H₁₃FN₂O₂S
• Número de CAS: 881970-80-5
• Peso molecular: 376.40
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 15991416
• NACRES: NA.77

Propiedades

• product name: Midkine Inhibitor, iMDK,
• Análisis: ≥98% (HPLC)
• Nivel de calidad: 100
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: off-white
• solubilidad: DMSO: 5 mg/mL
• temp. de almacenamiento: 2-8°C
• cadena SMILES: C1=CC=C2C(=C1)C=C(C(=O)O2)C3=CN4C=C(SC4=N3)CC5=CC=C(C=C5)F

Descripción

Descripción general

The midkine inhibitor, iMDK, demonstrates strong antiproliferative and antitumor effects both in vitro and in vivo in non-small-cell lung cancer. It also induces apoptosis of primary effusion lymphoma through G2/M cell cycle arrest.

Aplicación

Midkine Inhibitor, iMDK may be used to study its anti-cancer activity on primary effusion lymphoma (PEL) in vitro.

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
Midkine

Reversible: yes

Envase

Packaged under inert gas

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Otras notas

Hao, H., et al. 2013. PLoS ONE8, e71093.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable