481486

NF-κB SN50M, Cell-Permeable Inactive Control Peptide

An inactive control for SN50 peptide.

• Sinónimos: NF-κB SN50M, Cell-Permeable Inactive Control Peptide, (AAVALLPAVLLALLAPVQRNGQKLMP)
• Fórmula empírica (notación de Hill): C₁₂₃H₂₁₅N₃₃O₃₀S
• Peso molecular: 2668.29
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥97% (HPLC)
• Formulario: lyophilized
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic)
• solubilidad: water: 5 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys³⁶³ and Gly for Arg³⁶⁴ in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
an inactive control for SN50 peptide

Product does not compete with ATP.

Reversible: no

Envase

Yes

Advertencia

Toxicity: Standard Handling (A)

Secuencia

H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH

Forma física

Supplied as a trifluoroacetate salt.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.

Otras notas

Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.

Información legal

Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable