370695

GW1929

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).

• Sinónimos: GW1929, PPAR Agonist V, PPARγ Agonist IV
• Fórmula empírica (notación de Hill): C₃₀H₂₉N₃O₄
• Número de CAS: 196808-24-9
• Peso molecular: 495.57
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Formulario: crystalline solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; protect from light
• color: yellow
• solubilidad: DMSO: 100 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C
• InChI: 1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1
• Clave InChI: QTQMRBZOBKYXCG-MHZLTWQESA-N

Descripción

Descripción general

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine PPARγ and 6.2 nM for human PPARγ in cell-based transactivation assays).

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).

Acciones bioquímicas o fisiológicas

Cell permeable: no

EC50 = 13 nM as peroxisome proliferator-activated receptor γ (PPARγ) agonist for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays

Primary Target
Peroxisome proliferator-activated receptor γ (PPARγ) agonist

Product does not compete with ATP.

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Otras notas

Han, S., et al. 2004. Clin. Cancer Res.10, 1911.
Willson, T.M., et al. 2000. J. Med. Chem.43, 527.
Brown, K.K., et al. 1999. Diabetes48, 1415.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1