345250

N-Acetyllactosamine

A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.

• Sinónimos: N-Acetyllactosamine, O-β-D-Galactopyranosyl-β1,4-2-acetamido-2-deoxy-D-glucose, Galβ1,4GlcNAc, LacNAc
• Fórmula empírica (notación de Hill): C₁₄H₂₅NO₁₁
• Número de CAS: 32181-59-2
• Peso molecular: 383.35
• Número MDL: MFCD00063785
• Código UNSPSC: 12352201

Propiedades

• Nivel de calidad: 100
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• color: white to off-white
• solubilidad: water: 5 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 2-8°C
• InChI: 1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13-,14+/m1/s1
• Clave InChI: KFEUJDWYNGMDBV-LODBTCKLSA-N

Descripción

Descripción general

A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.

Aplicación

• Mass Spectrometry Analysis of Glycopeptides Enriched by Anion Exchange-Mediated Methods Reveals PolyLacNAc-Extended N-Glycans in Integrins and Tetraspanins in Melanoma Cells.: This research demonstrates the application of mass spectrometry in identifying N-acetyllactosamine extensions on glycoproteins in melanoma cells, providing insights into cellular adhesion and signaling mechanisms (Čaval et al., 2024).

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Nota de análisis

Single spot by TLC

Otras notas

Gunnarsson, A., et al. 1984. Infect. Immun.45, 41.
Loomes, L.M., et al. 1984. Nature307, 560.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable