317505

1,2-Dioctanoyl-sn-glycerol

Cell-permeable activator of protein kinase C (PKC).

• Sinónimos: 1,2-Dioctanoyl-sn-glycerol, DOG, PKC Activator IV
• Fórmula empírica (notación de Hill): C₁₉H₃₆O₅
• Número de CAS: 60514-48-9
• Peso molecular: 344.49
• Código UNSPSC: 12352200
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• formulario: oil
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• color: clear colorless
• solubilidad: chloroform: soluble; ethyl acetate: soluble
• Condiciones de envío: wet ice
• temp. de almacenamiento: −70°C
• InChI: 1S/C19H36O5/c1-3-5-7-9-11-13-18(21)23-16-17(15-20)24-19(22)14-12-10-8-6-4-2/h17,20H,3-16H2,1-2H3/t17-/m0/s1
• Clave InChI: ZQBULZYTDGUSSK-KRWDZBQOSA-N

Descripción

Descripción general

Cell-permeable activator of protein kinase C (PKC). Exhibits lower affinity for PKC_α than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Cell-permeable activator of protein kinase C; however, it has lower affinity for PKCa than for other isozymes. Shown to mimic the effects of tumor-promoting phorbol diesters on mitogenesis and epidermal growth factor binding and action in intact cells.

Acciones bioquímicas o fisiológicas

Cell permeable: yes

Primary Target
Protein kinase C

Reversible: no

Envase

Packaged under inert gas

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Unstable in solution; reconstitute just prior to use.

Nota de análisis

Single spot by TLC

Otras notas

Ferro, T.J., et al. 1993. Am. J. Physiol. 264, L7.
MacEwan, D.J., et al. 1993. Eur. J. Pharmacol. 246, 9.
Davis, R.J. 1985. J. Biol. Chem.260, 1562.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable