233493

Coagulation Factor α-XIIa, Human Plasma

Coagulation Factor α-XIIa, Human Plasma, is a native coagulation factor α-XIIa prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation.

• Sinónimos: Coagulation factor
• Código UNSPSC: 12352202
• NACRES: NA.25

Propiedades

• Nivel de calidad: 100
• formulario: liquid
• actividad específica: 50 units/mg protein (clotting assay)
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; avoid repeated freeze/thaw cycles
• Condiciones de envío: wet ice
• temp. de almacenamiento: −70°C

Descripción

Descripción general

Native coagulation factor α-XIIa from human plasma prepared from homogeneous Factor XII using dextran sulfate. Dextran sulfate is removed after activation. α-XIIa is a serine protease responsible for activation of Factor XI to Factor XIa. Factor XIIa and prekallikrein are thought to be involved in a reciprocal activation mechanism whereby Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to Factor XIIa.

Envase

Please refer to vial label for lot-specific concentration.

Advertencia

Toxicity: Standard Handling (A)

Forma física

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Nota de preparación

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Following initial thaw, aliquot and freeze (-70°C).

Nota de análisis

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

homogeneous by SDS-PAGE

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable