178221

α₂-Antiplasmin, Human Plasma

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.

• Sinónimos: α₂-Protease Inhibitor, Primary Plasmin Inhibitor
• Código UNSPSC: 12352202
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Análisis: ≥95% (SDS-PAGE)
• formulario: solid
• actividad específica: ≥5 IU/mg protein
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze
• Condiciones de envío: ambient
• temp. de almacenamiento: −20°C

Descripción

Descripción general

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.

Acciones bioquímicas o fisiológicas

Cell permeable: no

Primary Target
Plasminogen activator-induced lysis of fibrin clots

Product does not compete with ATP.

Reversible: no

Advertencia

Toxicity: Standard Handling (A)

Definición de unidad

One Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-pNA as substrate at 25°C, pH 7.8

Forma física

Lyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.

Nota de preparación

Please refer to the vial label for the lot-specific reconstitution volume.

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitución

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Otras notas

Schaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
Aoki, N., et al. 1980. Blood 55, 483.
Saito, H., et al. 1974. Circ. Res.34, 641.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable