14-845-M
PIP5K1γ Protein, active, 10 µg
Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.
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About This Item
Código UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.41
Productos recomendados
origen biológico
human
Nivel de calidad
recombinante
expressed in baculovirus infected Sf21 cells
mol peso
Mw 77 kDa
fabricante / nombre comercial
Upstate®
técnicas
activity assay: suitable (kinase)
Nº de acceso NCBI
Nº de acceso UniProt
Información sobre el gen
human ... PIP5K1C(23396)
Descripción general
N-terminal 6His-tagged, recombinant human PIP5K1γ, full length.
Product Source: Expressed by baculovirus in Sf21 insect cells
Aplicación
Active, N-terminal 6His-tagged, recombinant human PIP5K1γ, full length. For use in Kinase Assays.
Research Category
Signaling
Signaling
Research Sub Category
Oncology
Inflammation & Autoimmune Mechanisms
Diabetes
Alzheimer′s Disease
Neurodegenerative Diseases
Oncology
Inflammation & Autoimmune Mechanisms
Diabetes
Alzheimer′s Disease
Neurodegenerative Diseases
Acciones bioquímicas o fisiológicas
Protein Target: PIP5K1γ
Target Sub-Family: PIPK
Envase
Also available in 250μg size as catalog # 14-845M - Call for pricing and availability.
Calidad
Routinely evaluated in the PIProfiler.
Forma física
10µg of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution.
Immobilized metal affinity chromatography (IMAC)
Almacenamiento y estabilidad
6 months at -70°C
Otras notas
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Información legal
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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Development of a High-Throughput Screening Assay to Identify Inhibitors of the Lipid Kinase PIP5K1C.
Brittany D Wright et al.
Journal of biomolecular screening, 20(5), 655-662 (2014-12-24)
Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) regulate a variety of cellular processes, including signaling through G protein-coupled receptors (GPCRs), endocytosis, exocytosis, and cell migration. These lipid kinases synthesize phosphatidylinositol 4,5-bisphosphate (PIP2) from phosphatidylinositol 4-phosphate [PI(4)P]. Because small-molecule inhibitors of these lipid kinases
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