14-746-M

Src (1-530) Protein, active, 10 µg

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Propiedades

• origen biológico: human
• Nivel de calidad: 100
• mol peso: M_w 61.7 kDa
• fabricante / nombre comercial: Upstate^®
• técnicas: activity assay: suitable (kinase)
• Nº de acceso GenBank: K03218
• Nº de acceso UniProt: P05480 (mouse); P12931; Q9WUD9 (rat)
• Información sobre el gen: human ... SRC(6714)

Descripción

Descripción general

N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.

Product Source: Expressed by baculovirus in Sf21 insect cells.

The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.

Aplicación

Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.

Research Category
Metabolism

Research Sub Category
Cardiovascular Disease

Metabolic Disorders

Acciones bioquímicas o fisiológicas

Protein Target: Src

Target Sub-Family: TK

Envase

Also available in 250μg size as catalog # 14-746M - Call for pricing and availability.

Forma física

50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution

Ni²⁺/NTA-agarose

Almacenamiento y estabilidad

6 months at -70°C from date of shipment.

Otras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Información legal

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable