14-448-M

Cdk2/Cyclin A Protein, active, 10 µg

Active, C-terminal His6-tagged human full length Cdk2 & N-terminal GST-tagged human full length Cyclin A, for use in Kinase Assays.

• Código UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

Propiedades

• origen biológico: human
• Nivel de calidad: 100
• recombinante: expressed in baculovirus infected Sf21 cells
• Línea del producto: Upstate^®
• actividad específica: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• mol peso: M_w 35 kDa
• purificado por: (The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose)
• reactividad de especies: human
• fabricante / nombre comercial: Upstate^®
• técnicas: activity assay: suitable (kinase)
• nº de acceso: (FUNCTION: SwissProt: P24941 # Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2. ); NM_001798.2
• Nº de acceso NCBI: NM_001798.2; NM_052827.1
• Nº de acceso UniProt: P24941

Descripción

Descripción general

C-terminal His6-tagged human full length cdk2, and N-terminal GST-tagged human full length cyclin A

Acciones bioquímicas o fisiológicas

Protein Target: CDK2/cyclinA

Target Sub-Family: CMGC

Envase

Also available in 10 μg size and in bulk

Also available in 250μg size, please inquire for pricing and availability.

Calidad

routinely evaluated by phosphorylation of Histone H1

Descripción de destino

CDK2/cyclinA

Ligadura / enlace

Replaces: 14-407

Forma física

The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose^™ and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose

Almacenamiento y estabilidad

6 months at -70°C

Otras notas

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Información legal

Sepharose is a trademark of Cytiva

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H317
• Consejos de prudencia: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Clasificaciones de peligro: Skin Sens. 1
• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°C): Not applicable