1.37148

Trietanolamina

EMPROVE^® EXPERT, Ph. Eur., JPE, NF

• Sinónimos: 2,2′, 2′′-Nitrilotrietanol, Tris(2-hidroxietil)amina
• Fórmula lineal: (HOCH₂CH₂)₃N
• Número de CAS: 102-71-6
• Peso molecular: 149.19
• Beilstein: 1699263
• Número MDL: MFCD00002855
• Código UNSPSC: 12352104

Propiedades

• Agency: JPE; NF; Ph. Eur.
• Nivel de calidad: 500
• densidad de vapor: 5.14 (vs air)
• presión de vapor: 0.01 mmHg ( 20 °C)
• Línea del producto: EMPROVE^® EXPERT
• Formulario: liquid
• temp. de autoignición: 600 °F
• lim. expl.: 8.5 %
• técnicas: API processing | cocrystal formation: suitable
• índice de refracción: n20/D 1.485 (lit.)
• intervalo de pH útil: 7.3-8.3
• pKa (25 °C): 7.8
• bp: 190-193 °C/5 mmHg (lit.)
• mp: 17.9-21 °C (lit.)
• densidad: 1.124 g/mL at 25 °C (lit.)
• aplicaciones: liquid formulation; pharmaceutical; semi-solid formulation
• temp. de almacenamiento: 2-25°C
• cadena SMILES: OCCN(CCO)CCO
• InChI: 1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2
• Clave InChI: GSEJCLTVZPLZKY-UHFFFAOYSA-N

Descripción

Descripción general

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicación

Triethanolamine (Trolamine) is a tertiary amine that acts as a basic buffer component, typically used as a final formulation buffer for small molecules pharmaceuticals. It may also be used as a process buffer in cell lysis and biomolecule downstream chromatography.
As a multi-compendial product, Triethanolamine (Trolamine) Emprove^® Expert meets the N-nitrosodiethanolamine limits required by Ph Eur. Also, low microbial and endotoxin limits facilitate the use of this product in high-risk applications.

Información legal

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 354.2 °F - closed cup
• Punto de inflamabilidad (°C): 179 °C - closed cup