1.08121

Bromocresol green

pH indicator, ACS, Reag. Ph Eur

• Sinónimos: Bromocresol green, 3,3′,5,5′-Tetrabromo-m-cresolsulfonphthalein, BCG
• Fórmula empírica (notación de Hill): C₂₁H₁₄Br₄O₅S
• Número de CAS: 76-60-8
• Peso molecular: 698.01
• Número MDL: MFCD00005874
• Código UNSPSC: 41116100
• Número índice de la CE: 200-972-8
• NACRES: NB.21

Propiedades

• product name: Bromocresol green, indicator ACS,Reag. Ph Eur
• grado: ACS reagent
• Nivel de calidad: 200
• Agency: reag. Ph. Eur.
• formulario: solid
• pérdida: ≤3% loss on drying, 110°C
• visual transition interval: 3.8-5.4, yellow-green to blue
• mp: 217-218 °C
• densidad aparente: 350 kg/m³
• temp. de almacenamiento: no temp limit
• InChI: 1S/C21H14Br4O5S/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21/h3-8,26-27H,1-2H3
• Clave InChI: FRPHFZCDPYBUAU-UHFFFAOYSA-N

Descripción

Aplicación

• Sensitive and selective spectrophotometric assay of piroxicam in pure form, capsule and human blood serum samples via ion-pair complex formation.: This study presents a sensitive spectrophotometric method for determining piroxicam in various forms by forming an ion-pair complex with bromocresol green. This method enhances the accuracy and selectivity of piroxicam assays, providing valuable applications in pharmaceutical analysis and clinical diagnostics (Alizadeh & Keyhanian, 2014).


• A high-throughput colorimetric assay to measure the activity of glutamate decarboxylase.: Bromocresol green is utilized in a high-throughput colorimetric assay to measure the activity of glutamate decarboxylase. This assay is crucial for biochemical studies involving enzyme kinetics and could be applied in drug discovery and metabolic engineering research (Yu et al., 2011).


• Spectrophotometric and HPLC determinations of anti-diabetic drugs, rosiglitazone maleate and metformin hydrochloride, in pure form and in pharmaceutical preparations.: The use of bromocresol green in spectrophotometric and HPLC methods enhances the detection and quantification of anti-diabetic drugs. This research is vital for ensuring the quality and efficacy of pharmaceutical products (Onal, 2009).


• Spectrophotometric determination of lamotrigine in pharmaceutical preparations and urine by charge-transfer complexation.: Bromocresol green is employed in the spectrophotometric determination of lamotrigine, facilitating the analysis of this antiepileptic drug in pharmaceutical and biological samples. This application is essential for therapeutic drug monitoring and pharmaceutical quality control (Alizadeh et al., 2008).

Nota de análisis

Transition range: pH 3.8 - pH 5.4yellowish green - blue
Appearance of solution: passes test
Loss on drying (110 °C): ≤ 3
Transition range (according to ACS): passes test
Sensitivity test: passes test

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable