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Merck
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Key Documents

09-143

Sigma-Aldrich

Anti-Brk Antibody

Upstate®, from rabbit

Sinónimos:

PTK6, protein tyrosine kinase 6, breast tumor kinase, protein-tyrosine kinase BRK

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

human

fabricante / nombre comercial

Upstate®

técnicas

western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... PTK6(5753)

Especificidad

Recognizes Brk (breast tumor kinase, PTK6) at approximately 52 kDa. It can also recognize the 73 kDa ELF-related protein that shares 70% homology with the immunizing peptide.

Inmunógeno

KLH conjugated synthetic peptide corresponding to the N-terminal region of human Brk.

Aplicación

Detect Brk using this Anti-Brk Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Calidad

Routinely evaluated by immunoblot.

Descripción de destino

52 kDa

Forma física

50 µg of affinity purified rabbit polyclonal IgG in 0.02 M PBS, 250 mM sodium chloride containing 0.1% sodium azide.
ImmunoAffinity Purified

Almacenamiento y estabilidad

Store for 1 year at 2-8°C from date of shipment.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Growth response of Escherichia coli ATCC 35218 adapted to several concentrations of sodium benzoate and potassium sorbate.
Santiesteban-Lopez NA, Rosales M, Palou E, Lopez-Malo A
Journal of Food Protection null
Andrea Haegebarth et al.
Cell cycle (Georgetown, Tex.), 4(9), 1239-1246 (2005-08-06)
The intracellular tyrosine kinase Brk is expressed in regenerating epithelial tissues with highest levels in the gastrointestinal tract and skin. In these tissues, Brk is restricted to epithelial cells that are exiting the cell cycle and undergoing terminal differentiation. While
Haoqun Qiu et al.
The Journal of biological chemistry, 277(37), 34634-34641 (2002-07-18)
Brk (breast tumor kinase) is a nonreceptor tyrosine kinase that is most closely related to the Frk family of kinases, and more distantly to Src family kinases. Brk was originally identified in a screen for tyrosine kinases that are overexpressed
Monika Kasprzycka et al.
The American journal of pathology, 168(5), 1631-1641 (2006-05-03)
Tyrosine kinases play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been shown to mediate malignant cell transformation. Here we describe constitutive expression of the protein tyrosine kinase Brk in a large proportion of cutaneous
Haoqun Qiu et al.
Oncogene, 24(36), 5656-5664 (2005-05-05)
Breast tumor kinase (Brk) is a member of the Frk family of nonreceptor tyrosine kinases that is overexpressed in a high percentage of human breast tumors. The downstream substrates and effectors of Brk remain largely unidentified. In this study, we

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