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Merck
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Key Documents

07-601

Sigma-Aldrich

Anti-TTF-1 Antibody

serum, Upstate®

Sinónimos:

Anti-BCH, Anti-BHC, Anti-NK-2, Anti-NKX2.1, Anti-NKX2A, Anti-NMTC1, Anti-T/EBP, Anti-TEBP, Anti-TITF1, Anti-TTF-1, Anti-TTF1

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

mouse, rat, human

fabricante / nombre comercial

Upstate®

técnicas

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... A1CF(29974)

Especificidad

TTF-1

Inmunógeno

6His fusion protein corresponding to full-length TTF-1 (Thyroid transcription factor 1, also known as Thyroid nuclear factor 1, Homeobox protein Nkx-2.1)

Aplicación

Anti-TTF-1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of TTF-1 & has been validated in IP, WB & IHC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Calidad

routinely evaluated by immunoblot on nuclear extract from H441 human lung epithelial cells

Descripción de destino

42kDa

Ligadura / enlace

Replaces: MABE513

Forma física

Serum
rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%

Almacenamiento y estabilidad

2 years at -20°C

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Mario DeFelice et al.
The Journal of biological chemistry, 278(37), 35574-35583 (2003-06-28)
Thyroid transcription factor-1 (TTF-1) is a 43-kDa, phosphorylated member of the Nkx2 family of homeodomain-containing proteins expressed selectively in lung, thyroid, and the central nervous system. To assess the role of TTF-1 and its phosphorylation during lung morphogenesis, mice bearing
R J Bohinski et al.
Journal of neuro-oncology, 40(3), 227-231 (1999-03-05)
Determining the primary site of a cerebral metastatic adenocarcinoma is complicated by the histologic similarity of most adenocarcinomas. Thyroid Transcription Factor-1 (TTF-1) is a highly specific marker of peripheral airway cell neoplasms. Formalin fixed tissue from 30 patients with brain
Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.
Yuxia Cao,Tiffany Vo,Guetchyn Millien,Jean-Bosco Tagne,Darrell Kotton,Robert J Mason et al.
The Journal of Biological Chemistry null
A Khoor et al.
Human pathology, 30(6), 695-700 (1999-06-22)
Differentiation of malignant mesothelioma from adenocarcinoma, particularly from a lung primary, remains a difficult diagnostic problem. Surfactant protein B precursor (pro-SP-B) and thyroid transcription factor 1 (ITF-1) are expressed selectively in the normal respiratory epithelium and in adenocarcinomas of the
Jean-Bosco Tagne et al.
PloS one, 7(1), e29907-e29907 (2012-01-14)
The homeodomain transcription factor Nkx2-1 is essential for normal lung development and homeostasis. In lung tumors, it is considered a lineage survival oncogene and prognostic factor depending on its expression levels. The target genes directly bound by Nkx2-1, that could

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