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Merck
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Documentos clave

07-543

Sigma-Aldrich

Anti-p19 ARF Antibody

Upstate®, from rabbit

Sinónimos:

Anti-ARF, Anti-CDK4I, Anti-CDKN2, Anti-CMM2, Anti-INK4, Anti-INK4A, Anti-MLM, Anti-MTS-1, Anti-MTS1, Anti-P14, Anti-P14ARF, Anti-P16, Anti-P16-INK4A, Anti-P16INK4, Anti-P16INK4A, Anti-P19, Anti-P19ARF, Anti-TP16

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

100

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

rat, mouse

fabricante / nombre comercial

Upstate®

técnicas

immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG

Nº de acceso UniProt

Q8N726

Condiciones de envío

wet ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

mouse ... Cdkn2A(12578)
rat ... Cdkn2A(25163)

Especificidad

p19 ARF

Inmunógeno

Full length mouse p19 ARF fused to GST.

Aplicación

Detect p19 ARF with Anti-p19 ARF Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP & WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Calidad

Routinely evaluated by immunoblot with lysates from p53 knockout MEF cells.

Descripción de destino

19kDa

Forma física

ImmunoAffinity Purified

Almacenamiento y estabilidad

2 years at -20°C from date of shipment

Nota de análisis

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Opcional

Referencia del producto
Descripción
Precios

Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Shubhankar Suman et al.
Aging, 5(8), 607-622 (2013-08-10)
Despite recent epidemiological evidences linking radiation exposure and a number of human ailments including cancer, mechanistic understanding of how radiation inflicts long-term changes in cerebral cortex, which regulates important neuronal functions, remains obscure. The current study dissects molecular events relevant
p19ARF directly and differentially controls the functions of c-Myc independently of p53.
Ying Qi, Mark A Gregory, Zhaoliang Li, Jeffrey P Brousal, Kimberly West, Stephen R Hann
Nature null
Hui-Yi Kua et al.
Nature cell biology, 14(7), 727-737 (2012-06-26)
Defects in stem cell renewal or progenitor cell expansion underlie ageing-related diseases such as osteoporosis. Yet much remains unclear about the mechanisms regulating progenitor expansion. Here we show that the tyrosine kinase c-Abl plays an important role in osteoprogenitor expansion.
S Kitajima et al.
Oncogene, 30(6), 737-750 (2010-10-05)
The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) gene had been isolated as an antagonist to RAS signaling; however, the mechanism of its action is not clear. In this study, the effect of loss of RECK function was assessed in
Nicolas Jullien et al.
PloS one, 10(3), e0120010-e0120010 (2015-03-31)
To test the role of wtPIT-1 (PITWT) or PIT-1 (R271W) (PIT271) in somatolactotroph cells, we established, using inducible lentiviral vectors, sublines of GH4C1 somatotroph cells that allow the blockade of the expression of endogenous PIT-1 and/or the expression of PITWT

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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