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Merck
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Documentos clave

07-540

Sigma-Aldrich

Anti-acetyl-Histone H3 (Lys36) Antibody

serum, Upstate®

Sinónimos:

H3K36Ac, Histone H3 (acetyl K36)

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

serum

tipo de anticuerpo

primary antibodies

clon

polyclonal

reactividad de especies

human

fabricante / nombre comercial

Upstate®

técnicas

multiplexing: suitable
western blot: suitable

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

wet ice

modificación del objetivo postraduccional

acetylation (Lys36)

Información sobre el gen

human ... H3F3B(3021)

Especificidad

Broad species cross reactivity is expected
Recognizes Histone H3 when acetylated on Lys36

Inmunógeno

KLH-conjugated, synthetic peptide containing the sequence ...GV[AcK]KP... in which [AcK] corresponds to acetyl-lysine 36 of human histone H3.

Aplicación

Suggested dilutions:
Western Blot: 1:5000 - 1:20,000

ChIP Analysis: A representative lot was used by an independent laboratory for ChIP (Gatta, R., et al. (2011). Epigenetics. 6(4):526-534.)
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones
Use Anti-acetyl-Histone H3 (Lys36) Antibody (Rabbit Polyclonal Antibody) validated in WB, Mplex to detect acetyl-Histone H3 (Lys36) also known as H3K36Ac, Histone H3 (acetyl K36).

Calidad

Routinely evaluated by immunoblot.

Descripción de destino

~17kDa

Forma física

100μl of rabbit antiserum containing 0.05% sodium azide and 30% glycerol.
Antiserum

Almacenamiento y estabilidad

2 years at -20°C from date of shipment

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

12 - Non Combustible Liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.
Thapa, A; Morris, L; Xu, J; Ma, H; Michalakis, S; Biel, M; Ding, XQ
The Journal of Biological Chemistry null
Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy.
Thalacker-Mercer, A; Stec, M; Cui, X; Cross, J; Windham, S; Bamman, M
Physiological Genomics null
Anton Eberharter et al.
EMBO reports, 3(3), 224-229 (2002-03-08)
The organization of eukaryotic chromatin has a major impact on all nuclear processes involving DNA substrates. Gene expression is affected by the positioning of individual nucleosomes relative to regulatory sequence elements, by the folding of the nucleosomal fiber into higher-order
Raffaella Gatta et al.
Epigenetics, 6(4), 526-534 (2011-02-10)
Histones post-translational modifications (PTMs) are crucial for transcriptional control, defining positive and negative chromatin territories. We previously described an extensive methylation-acetylation switch on cell cycle promoters using a single nucleosome ChIP assay. A key issue is how PTMs are locally
James N Psathas et al.
Molecular and cellular biology, 29(24), 6413-6426 (2009-10-14)
Posttranslational modifications to histones have been studied extensively, but the requirement for the residues within the tails for different stages of transcription is less clear. Using RNR3 as a model, we found that the residues within the N terminus of

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