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Merck
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07-140

Sigma-Aldrich

Anti-STAT2 Antibody

Upstate®, from rabbit

Sinónimos:

Anti-IMD44, Anti-ISGF-3, Anti-P113, Anti-PTORCH3, Anti-STAT113

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

forma del anticuerpo

affinity isolated antibody

tipo de anticuerpo

primary antibodies

clon

polyclonal

purificado por

affinity chromatography

reactividad de especies

mouse

fabricante / nombre comercial

Upstate®

técnicas

electrophoretic mobility shift assay: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotipo

IgG

Nº de acceso NCBI

Nº de acceso UniProt

Condiciones de envío

dry ice

modificación del objetivo postraduccional

unmodified

Información sobre el gen

human ... STAT2(6773)

Especificidad

STAT2

Inmunógeno

GST-fusion protein corresponding to residues 672-925 of murine STAT2

Aplicación

Anti-STAT2 Antibody is a Rabbit Polyclonal Antibody for detection of STAT2 also known as Signal Transducer & Activator of Transcription 2 & has been tested in EMSA, IP, WB, ICC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Calidad

routinely evaluated by immunoblot on

Descripción de destino

130kDa

Forma física

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Affinity Chromatography

Almacenamiento y estabilidad

2 years at -20°C

Nota de análisis

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

Información legal

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.
Zhu Guo, Sanjay Garg, Karen M Hill, Lakshmi Jayashankar, Myesha R Mooney, Mary Hoelscher et al.
Journal of immunology (Baltimore, Md. : 1950) (1950)
Connie C Qiu et al.
Oncoimmunology, 10(1), 1860477-1860477 (2021-01-19)
STAT2 is a central component of the ISGF3 transcriptional complex downstream of type I interferon (IFN-I) signaling. The significance of in vivo IFN-I/STAT1 signals in cDCs is well-established in the generation of antitumor cytotoxic T cell (CTL) responses. However, the role
Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
Zurney, J; Kobayashi, T; Holm, GH; Dermody, TS; Sherry, B
Journal of virology null
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.
Lagor, WR; Fields, DW; Bauer, RC; Crawford, A; Abt, MC; Artis, D; Wherry, EJ; Rader, DJ
Atherosclerosis null
M Matsumoto et al.
Biological chemistry, 380(6), 699-703 (1999-08-03)
The interferon-stimulated gene factor 3 (ISGF3) transcription factor has been extensively studied in the context of the type I interferon (IFN-alpha/beta)-mediated antiviral response; it consists of the major DNA-binding component p48, and the signal transducers and activators of transcription (Stat)1

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