P-008

Phenobarbital solution

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Sinónimos: 5-Ethyl-5-phenylbarbituric acid solution
• Fórmula empírica (notación de Hill): C₁₂H₁₂N₂O₃
• Número de CAS: 50-06-6
• Peso molecular: 232.24
• Número MDL: MFCD00066494
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329820008
• NACRES: NA.24

Propiedades

• grado: certified reference material
• formulario: liquid
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• drug control: Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
• concentración: 1 mg/mL in methanol
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: forensics and toxicology
• formato: single component solution
• temp. de almacenamiento: -10 to -25°C
• cadena SMILES: CCC1(C(=O)NC(=O)NC1=O)c2ccccc2
• InChI: 1S/C12H12N2O3/c1-2-12(8-6-4-3-5-7-8)9(15)13-11(17)14-10(12)16/h3-7H,2H2,1H3,(H2,13,14,15,16,17)
• Clave InChI: DDBREPKUVSBGFI-UHFFFAOYSA-N

Descripción

Descripción general

Phenobarbital is the oldest and most widely used barbiturate. The drug is an anticonvulsant approved for treatment of all seizure types with the exception of absence seizures. This certified solution standard is suitable as starting material for the preparation of calibrators and controls in phenobarbital testing by GC/MS or LC-MS/MS.

Aplicación

• Fabrication of a Surface Molecularly Imprinted Polymer Membrane: Phenobarbital is utilized in the development of molecularly imprinted polymer membranes for the selective separation and extraction of various pharmaceutical compounds, enhancing the precision and efficiency of drug monitoring in clinical settings. This application leverages the specific binding properties of Phenobarbital to improve sample preparation techniques for complex biological matrices (Zhao et al., 2024).


• An Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry-Based Reference Measurement Procedure: Phenobarbital′s role in establishing reference measurement procedures underscores its importance in ensuring the accuracy and reliability of drug quantification in clinical laboratories. This application supports the standardization of laboratory measurements, critical for patient care and therapeutic monitoring (Schierscher et al., 2024).

Productos recomendados

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Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS06,GHS08
• Palabra de señalización: Danger
• Frases de peligro: H225,H301 + H311 + H331,H370
• Consejos de prudencia: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Clasificaciones de peligro: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Órganos de actuación: Eyes,Central nervous system
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 49.5 °F - closed cup
• Punto de inflamabilidad (°C): 9.7 °C - closed cup