P-121

Prednisolone solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Fórmula empírica (notación de Hill): C₂₁H₂₈O₅
• Número de CAS: 50-24-8
• Peso molecular: 360.44
• Número MDL: MFCD00003649
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329820079
• NACRES: NA.24

Propiedades

• grado: certified reference material
• Nivel de calidad: 300
• Formulario: liquid
• Características: Snap-N-Spike^®/Snap-N-Shoot^®
• envase: ampule of 1 mL
• fabricante / nombre comercial: Cerilliant^®
• concentración: 100 μg/mL in acetonitrile
• técnicas: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicaciones: clinical testing
• Formato: single component solution
• temp. de almacenamiento: −20°C
• cadena SMILES: O[C@]1([C@@]2([C@H]([C@H]3[C@@H]([C@@]4(C(=CC(=O)C=C4)CC3)C)[C@H](C2)O)CC1)C)C(=O)CO
• InChI: 1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• Clave InChI: OIGNJSKKLXVSLS-VWUMJDOOSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

Prednisolone is a synthetic glucocorticoid and derivative of cortisol which is used to treat a variety of inflammatory and auto-immune conditions. It is the active metabolite of the drug prednisone and is used especially in patients with liver failure, as these individuals are unable to metabolise prednisone into prednisolone. This Certified Spiking Solution^® is suitable for use as starting materials in the preparation of calibrators and controls for prednisolone testing methods by GC/MS or LC-MS/MS.

Aplicación

• Casein hydrolysate as a rapid and/or enteric dissolving additive for oral drugs.: This study investigates the use of Prednisolone solution in formulating rapid and enteric dissolving oral drugs. It highlights the importance of Prednisolone liquid for biochemical assays and in vitro glucocorticoid studies, demonstrating its utility in pharmaceutical research applications (Imai et al., 1998).

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H302 + H312 + H332,H319
• Consejos de prudencia: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): 35.6 °F - closed cup
• Punto de inflamabilidad (°C): 2.0 °C - closed cup