A-916
7-Aminoclonazepam solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
Iniciar sesiónpara Ver la Fijación de precios por contrato y de la organización
About This Item
Fórmula empírica (notación de Hill):
C15H12ClN3O
Número de CAS:
Peso molecular:
285.73
Número MDL:
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
NACRES:
NA.24
Productos recomendados
grado
certified reference material
Nivel de calidad
formulario
liquid
Características
SNAP-N-SPIKE®, SNAP-N-SHOOT®
envase
ampule of 1 mL
fabricante / nombre comercial
Cerilliant®
concentración
1.0 mg/mL in acetonitrile
técnicas
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
aplicaciones
clinical testing
formato
single component solution
temp. de almacenamiento
2-8°C
cadena SMILES
NC1=CC=C2C(C(C3=C(Cl)C=CC=C3)=NCC(N2)=O)=C1
InChI
1S/C15H12ClN3O/c16-12-4-2-1-3-10(12)15-11-7-9(17)5-6-13(11)19-14(20)8-18-15/h1-7H,8,17H2,(H,19,20)
Clave InChI
HEFRPWRJTGLSSV-UHFFFAOYSA-N
¿Está buscando productos similares? Visita Guía de comparación de productos
Descripción general
This certified Snap-N-Spike® solution is suitable for use as a starting material in calibrators and controls for numerous GC/MS or LC/MS applications in forensic analysis, clinical toxicology and urine drug testing. As a major metabolite, 7-aminoclonazepam may be used to monitor use of the parent drug, clonazepam. Clonazepam, marketed as Klonopin® and Rivotril, is a long-acting benzodiazepine with anxiolytic, anticonvulsant, muscle relaxant, and hypnotic properties.
Aplicación
- 7-Aminoclonazepam as a Reference Standard in Forensic Toxicology: This benzodiazepine metabolite is critical for forensic applications, where it serves as a reference standard for the confirmation and quantitation of clonazepam in biological samples. Its reliable detection in toxicological screenings is crucial for legal and medical interpretations (Elenstål et al., 2023).
- Pharmacokinetic Studies with 7-Aminoclonazepam: In pharmacokinetics, 7-Aminoclonazepam is studied to understand the metabolic pathways of clonazepam, particularly its transformation and elimination in the human body. This research is vital for developing dosing regimens that optimize therapeutic outcomes while minimizing side effects (Øiestad et al., 2023).
- Stability Studies of 7-Aminoclonazepam: Stability testing of 7-Aminoclonazepam in various storage conditions provides essential data on how storage conditions affect the integrity of this compound. Such information ensures the accuracy and reliability of bioanalytical assays used in clinical and forensic settings (Dahlin & Petrides, 2022).
Información legal
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Klonopin is a registered trademark of Hoffmann-La Roche Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Producto relacionado
Referencia del producto
Descripción
Precios
Palabra de señalización
Danger
Frases de peligro
Clasificaciones de peligro
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Código de clase de almacenamiento
3 - Flammable liquids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
35.6 °F - closed cup
Punto de inflamabilidad (°C)
2 °C - closed cup
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Los clientes también vieron
Adam Negrusz et al.
Journal of analytical toxicology, 26(7), 471-478 (2002-11-09)
The objective of this paper was to determine whether benzodiazepine clonazepam (CLO) and its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in hair collected from healthy volunteers after receiving a single 3-mg dose of Klonopin (clonazepam). Such data would be
Adam Negrusz et al.
Analytical and bioanalytical chemistry, 376(8), 1198-1204 (2003-07-08)
The objective of this paper was to determine how long after administration of benzodiazepine clonazepam (CLO), its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in urine collected from 10 healthy volunteers who received a single 3-mg dose of Klonopin (clonazepam).
I Petters et al.
Journal of chromatography, 306, 241-248 (1984-03-09)
A high-performance liquid chromatographic method is reported for the determination of clonazepam and its metabolites 7-amino- and 7-acetamidoclonazepam. Extraction from buffered plasma is carried out at pH 9.5 with hexane-ethyl acetate (7:3) for clonazepam and with chloroform for the metabolites.
Albert A Elian
Forensic science international, 134(1), 54-56 (2003-07-05)
The ability of five commercially available enzyme-linked immunosorbent assay (ELISA) benzodiazepines to detect clonazepam and 7-aminoclonazepam in blood and urine was investigated. To determine the cross-reactivity of various ELISA assays, drug free blood and urine were fortified with clonazepam and
Marjorie Chèze et al.
Forensic science international, 145(2-3), 123-130 (2004-09-29)
The number of reports on drug facilitated crimes is increasing these last years. Apart from ethanol and cannabis, benzodiazepines (BZD) and analogs are the most common drugs reported to be used probably due to their amnesic and sedative properties. We
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico