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Merck

850182P

Avanti

08:0 PI(4)P

Avanti Research - A Croda Brand

Sinónimos:

PIP[4′](8:0/8:0)

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About This Item

Fórmula empírica (notación de Hill):
C25H54N2O16P2
Número de CAS:
Peso molecular:
700.65
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

descripción

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-4′-phosphate) (ammonium salt)

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 100 μg (with stopper and crimp cap (850182P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850182P-500ug))

fabricante / nombre comercial

Avanti Research - A Croda Brand

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])(O)=O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C25H48O16P2.2H3N/c1-3-5-7-9-11-13-18(26)37-15-17(39-19(27)14-12-10-8-6-4-2)16-38-43(35,36)41-25-22(30)20(28)24(21(29)23(25)31)40-42(32,33)34;;/h17,20-25,28-31H,3-16H2,1-2H3,(H,35,36)(H2,32,33,34);2*1H3/t17-,20-,21+,22-,23-,24+,25+;;/m1../s1

Clave InChI

GRYUDEZZGXKOJR-JHABFHEXSA-N

Descripción general

08:0 PIP is a phosphoinositol phosphate (PIP). Among prokaryotes, PI is synthesized by mycobacteria and few other bacterial genera.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Aplicación

08:0 PIP has been used to prepare multilamellar vesicle liposomes (MLV) for lipid binding assays. It is also suitable for use in the formation of protein-lipid tube and to examine fluorescence spectrum for analysing the PIP/sterol exchange properties of the Osh1 OSBP-related domain (ORD)

Acciones bioquímicas o fisiológicas

08:0 PIP can control ion channel activity. Phosphoinositol phosphates (PIPs) with short acyl chains, that are soluble in water can be used for reversible transport into the plasma membrane.

Envase

2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850182P-500ug)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

No data available

Punto de inflamabilidad (°C)

No data available


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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica
Perdomo D, et al.
Cellular Microbiology, 18(8), 1134-1152 (2016)
Short-chain phosphoinositide partitioning into plasma membrane models
Collins MD and Gordon SE
Biophysical Journal, 105(11), 2485-2494 (2013)
An endophilin-dynamin complex promotes budding of clathrin-coated vesicles during synaptic vesicle recycling
Sundborger A, et al.
Journal of Cell Science, 124(1), 133-143 (2011)
Structure of yeast OSBP-related protein Osh1 reveals key determinants for lipid transport and protein targeting at the nucleus-vacuole junction
Manik MK, et al.
Structure, 25(4), 617-629 (2017)
Structural basis for phosphatidylinositol-phosphate biosynthesis
Clarke OB, et al.
Nature Communications, 6, 8505-8505 (2015)

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