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840055P

Avanti

Liver PC

Avanti Research™ - A Croda Brand 840055P, powder

Sinónimos:

L-α-phosphatidylcholine (Liver, Bovine)

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About This Item

Número de CAS:
475662-36-3
Número MDL:
MFCD00674330
Código UNSPSC:
12352211
NACRES:
NA.25

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 25 mg (840055P-25mg)

fabricante / nombre comercial

Avanti Research™ - A Croda Brand 840055P

tipo de lípido

phosphoglycerides
phospholipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1

Clave InChI

FORFDCPQKJHEBF-VPUSDGANSA-N

Descripción general

Phosphatidylcholine (PC) has two fatty acid chains attached to a head group. Generally, PC has saturated fatty acid in the sn-1 position and unsaturated fatty acid in the sn-2 position. It has a quaternary ammonium group and a phosphate moiety in the head group, existing as a zwitterion in a wide range of pH.

Aplicación

Liver PC is suitable for use:
  • as a standard for quantitation of tumor derived lipids by thin layer chromatography
  • in the preparation of liposomes to mimic mammalian membranes
  • in lipid vesicle preparation to study intravesicular transfer of α-tocopherol fluorescent derivative (NBD-Toc)

Acciones bioquímicas o fisiológicas

Phosphatidylcholine (PC) plays a key role in the synthesis of second messenger and signaling molecules like diacyl glycerol, lysophosphatidic acid, phosphatidic acid and arachidonic acid. Liver PC has a saturated to unsaturated fatty acid ratio of 0.91.

Envase

5 mL Clear Glass Sealed Ampule (840055P-25mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

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Certificados de análisis (COA)

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Essentials of Medical Biochemistry: With Clinical Cases (2011)
Noncovalently and covalently bound lipid on the receptor for immunoglobulin E
Kinet JP, et al.
Biochemistry, 24(25), 7342-7348 (1985)
Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose
Moore DS, et al.
Biochimica et Biophysica Acta - Biomembranes, 1858(1), 104-115 (2016)
Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein
Zhang WX, et al.
Lipids, 44(7), 631-631 (2009)
Soyoun Kim et al.
PloS one, 10(3), e0121171-e0121171 (2015-03-25)
A number of peptide-based indicators have been identified and reported as potential apoptosis probes, offering great promise for early assessment of therapeutic efficacy in several types of cancer. Direct comparison of the newly developed probes with previously used ones would
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